MIAMI – The 2026 Concacaf Champions Cup continues with Deportivo Toluca FC hosting San Diego FC in the Second Leg of their Round of 16 series on Wednesday at Estadio Nemesio Díez in Toluca, Mexico.

The MLS side pulled off a massive 3-2 victory in the first leg despite receiving a pair of red cards and finishing the game with only nine players on the field.

David Vázquez notched a brace, and Anders Dreyer delivered the winner for San Diego. SDFC will be without two key players for this match as Marcus Ingvartsen and Manu Duah were sent off in the first leg.

Toluca’s goals both came from the penalty spot as Jesús Gallardo and Helinho converted successfully for the Liga MX champions.

San Diego became the first tournament debutant to defeat Toluca in Champions Cup history, ending the Mexican club’s four-match unbeaten streak against debutant teams. It also marked the fourth time a United States club earned a home victory scoring three goals against Mexican opposition in the tournament’s history.

The winner of this series on aggregate will advance to the Quarterfinals. Away goals serve as the first tiebreaker. If necessary, extra time and a penalty shootout will be played to decide a winner.

Looking Ahead to the Round of 16 Second Legs

Overall, it was the fifth time Toluca FC lost the first leg of a series, and the club has advanced only once: vs CF América in the 2002-03 Semifinals (lost 1-4 in the first leg and produced a remarkable 4-0 comeback in the second leg, securing the series 5-4 on aggregate).

Toluca was eliminated three times:

1972 vs CD Olimpia in the Semifinals (first leg 0-1, second leg 1-1, aggregate 2-1)

2010-11 vs CF Monterrey in the Quarterfinals (first leg 0-1, second leg 1-0, aggregate 2-0)

2019 vs Sporting Kansas City in the Round of 16 (first leg 3-0, second leg 0-2, aggregate 0-5).

It was the fourth time a United States club earned a home victory scoring three goals against a Mexican opponent in the history of the tournament (since 1962). Only one club was eliminated: New England Revolution vs Pumas UNAM in the 2022 Quarterfinals (first leg 3-0, second leg 3-0, aggregate 3-3, penalties 4-3).

Two clubs advanced:

Sporting Kansas City vs Toluca FC in the Round of 16 of 2019 (first leg 3-0, second leg 0-2, aggregate 5-0)

Seattle Sounders FC vs Club León in the Quarterfinals of 2022 (first leg 3-0, second leg 1-1, aggregate 4-1).

CCC Round of 16 Team Records

Toluca FC
Penalty shootout appearances: (2). (Win). (2-3 vs. Deportivo Saprissa in the Semifinal, single match of the 1998 edition after a 1-1 draw). (Win). (5-4 vs. San Jose Earthquakes in the Quarterfinals of the 2013-2014 edition after a 2-2 aggregate score: D 1-1 and D 1-1).
Hat-tricks: (1). Héctor Mancilla (CHI) vs. CD FAS (Matchday 11, Group D of 2010-2011).
Round of 16 appearances: 3 (2002-2003 vs. W Connection FC, 2019 vs. Sporting Kansas City, 2026 vs. San Diego FC).
Record in R16 history: GP-5 W-1 D-1 L-3 (GF-8 GA-13).
Top scorers in R16: Vicente Sánchez (URU) 2, Ariel Franco (ARG) 2.

San Diego FC
Penalty shootout appearances: (0).
Braces: (1). David Vázquez (USA) vs. Toluca FC (2026 Round of 16).
Round of 16 appearances: 1 (2026 vs. Toluca FC).
Record in R16 history: GP-1 W-1 D-0 L-0 (GF-3 GA-2).
Top scorers in R16: David Vázquez (USA) 2.