Santiago, who played in every match for Mexico at both the CONCACAF U-17 women's and U-20 women's championships in 2010, will be joined by senior national team defenders Ariana Romero, Bianca Sierra and Christina Murillo as well as forward Chrystal Martinez.
Head coach Roberto Medina also selected from 2010 U-17 graduates Christina Ferral, Fernanda Pina, Tanya Samarzich and Andrea Sanchez, as well as 2010 U-20 holdovers Ashley Kotero, Nayeli Rangel, Natalia Gomez Junco and Olivia Jimenez.
In addition to Santiago, Sierra was a member of the 2010 U-20 team that finished runner-up to the United States, while Murillo was with Santiago when Mexico was runner-up at the 2010 U-17 championship to Canada.
After finishing third twice and second the last time, Mexico will begin its bid for the CONCACAF U-20 women's crown Thursday against Jamaica at Estadio Rommel Fernandez in the nightcap of a doubleheader that also includes Canada vs. Haiti.
Mexico will be seeking one of three berths at the Under-20 Women's Cup in Japan and its fourth straight trip to the world finals.
Mexico's U-20 women's roster:
GOALKEEPERS: Cecilia Santiago, Rosa Mérida Medina.
DEFENDERS: Arianna Romero, Bianca Sierra, Christina Murillo, Ashley Kotero, Alejandra Amador, Cristina Ferral, Mariel Gutiérrez.
IDFIELDERS: Nayeli Rangel, Yamile Franco, Natalia Gómez Junco, Olivia Jiménez, Ariana Martínez.
ORWARDS: Tanya Samarzich, Chrystal Martínez, Briana López, Fernanda Piña, Andrea Sánchez, Daniela Solís.